Buclizine Hydrochloride

Name	buclizine dihydrochloride
Synonyms	buclodin aphilanr Buclizine HCl buclizinehydrochloride Buclizine Hydrochloride buclizine dihydrochloride Buclizine, dihydrochloride 1-(4-(tert-Butyl)benzyl)-4-((4-chlorophenyl)(phenyl)meth 1-p-chlorobenzhydryl-4-p-(t)-butylbenzylpiperazinedihydrochloride 1-(p-tert-butylbenzyl)-4-(p-chlorodiphenylmethyl)piperazinedihydrochloride 1-(p-tert-butylbenzyl)-4-(p-chloro-alpha-phenylbenzyl)-piperazindihydrochl 1-(p-tert-butylbenzyl-4-p-chloro-alpha-phenylbenzyl)piperazinedihydrochlorid 1-(4-tert-butylbenzyl)-4-[(4-chlorophenyl)(phenyl)methyl]piperazine dihydrochloride
CAS	129-74-8
EINECS	204-962-4
InChI	InChI=1/C28H33ClN2.2ClH/c1-28(2,3)25-13-9-22(10-14-25)21-30-17-19-31(20-18-30)27(23-7-5-4-6-8-23)24-11-15-26(29)16-12-24;;/h4-16,27H,17-21H2,1-3H3;2*1H

Molecular Formula	C28H35Cl3N2
Molar Mass	505.95
Melting Point	230-240°C
Boling Point	520.1°C at 760 mmHg
Flash Point	268.3°C
Solubility	Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly)
Vapor Presure	6.44E-11mmHg at 25°C
Appearance	grayish white powder
Color	white to beige
Storage Condition	Inert atmosphere,2-8°C
Stability	Hygroscopic
In vitro study	Buclizine hydrochloride, a piperazine derivative, is a sedative antihistamine with antimuscarinic and moderately sedative effects. Buclizine is used for the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness. In addition, it is used in the treatment of Vertigo diseases affecting the vestibular apparatus. Although the mechanism by which buclizine exerts its antiemetic and antidizziness effects has not been fully elucidated, its central anticholinergic effects are partly responsible. The drug inhibits labyrinthine excitability and vestibular stimulation, and it may affect the medullary chemoreceptor trigger zone. It also has anticholinergic, antihistaminic, central nervous system depressant, and local anesthetic effects.

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Multiple SpecificationsSpot supply

Product Name: BUCLIZINE, DIHYDROCHLORIDE Visit Supplier Webpage Request for quotation
CAS: 129-74-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

Wechat: 18301782025

Product Name: Buclizine dihydrochloride Request for quotation
CAS: 129-74-8
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228

Wechat: 13651600618
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Buclizine Hydrochloride
61260-10-4

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